KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPHP3
All Species:
0.61
Human Site:
S44
Identified Species:
1.48
UniProt:
Q7Z494
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z494
NP_694972.3
1330
150864
S44
K
A
R
L
L
R
N
S
F
R
R
G
A
G
A
Chimpanzee
Pan troglodytes
XP_516758
2073
234018
T57
A
K
A
R
C
C
A
T
R
S
A
R
R
G
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_863943
2040
230770
K35
C
E
I
P
V
E
V
K
P
K
A
R
L
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q7TNH6
1324
150168
L40
E
V
K
P
K
A
R
L
L
R
S
S
F
R
R
Rat
Rattus norvegicus
XP_343462
1325
150597
L40
E
V
K
P
K
A
R
L
L
R
S
S
F
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514031
1275
145541
A40
Q
T
M
S
L
E
L
A
G
E
N
S
L
G
K
Chicken
Gallus gallus
XP_418790
1315
149161
P36
E
I
P
V
E
V
K
P
K
A
R
L
L
R
G
Frog
Xenopus laevis
Q6AZT7
1300
148301
K35
I
P
V
E
V
K
P
K
A
R
L
L
R
S
S
Zebra Danio
Brachydanio rerio
XP_691073
1303
148244
K35
I
P
V
E
V
K
P
K
A
R
L
L
R
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203493
1012
113472
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
61.7
N.A.
61.5
N.A.
88.8
87.9
N.A.
78
83.9
76.9
69.9
N.A.
N.A.
N.A.
N.A.
30.9
Protein Similarity:
100
62.4
N.A.
63
N.A.
93.3
93.3
N.A.
86.2
90.7
86.5
82.9
N.A.
N.A.
N.A.
N.A.
49.1
P-Site Identity:
100
6.6
N.A.
0
N.A.
6.6
6.6
N.A.
13.3
6.6
6.6
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
13.3
N.A.
13.3
N.A.
20
20
N.A.
26.6
20
26.6
26.6
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
10
0
0
20
10
10
20
10
20
0
10
0
10
% A
% Cys:
10
0
0
0
10
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
30
10
0
20
10
20
0
0
0
10
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
0
20
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
10
0
0
10
0
30
20
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
20
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
10
20
0
20
20
10
30
10
10
0
0
0
0
10
% K
% Leu:
0
0
0
10
20
0
10
20
20
0
20
30
30
10
0
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
10
0
0
0
0
% N
% Pro:
0
20
10
30
0
0
20
10
10
0
0
0
0
0
0
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
10
10
0
10
20
0
10
50
20
20
30
30
30
% R
% Ser:
0
0
0
10
0
0
0
10
0
10
20
30
0
20
20
% S
% Thr:
0
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% T
% Val:
0
20
20
10
30
10
10
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _